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Therapeutic-drug

Treatment and Biomarker of Hepatocellular Carcinoma Caused by Sinusoid...

Inhibitor of the integrin αV‒CTGF axis, which is activated in response to increased hepatic sinusoid…

Macrophages as Drug Targets for Hypertension Treatment

Discovery of a new mechanism of hypertension induction and proposal for drug discovery collaboration…

Therapeutics for Fibrosis Targeting RIG-I

A drug candidate for the treatment of various fibrosis, incorporating a ligand for RIG-I, a pattern …

Cancer Metastasis Inhibitor

Target molecules and their inhibitors that control the survival and reactivation of disseminated tum…

Rett Syndrome Therapeutic Drug

We have recently discovered that an already approved small-molecule therapeutic drug is effective ag…

Collaborative Development of Therapeutic Medicine for Infectious Disea...

Small Molecule enhances Claudin-5 (CLDN5) function, which organizes tight junctions between vascular…

Enhancer of Anticancer Drug Taxanes

Small molecules that enhance the microtubule polymerization-promoting activity of anticancer drug ta…

Fusion Protein Anticancer Drug Targeting RAS

Fusion protein X, which combines a RAS-binding domain, a cell membrane-permeable peptide, and a thir…

Development of Phosphate Prodrug Compounds of Nucleic Acid Analogues

Development of fluoride-type phosphate prodrugs bearing fluorophosphoramidate as biocompatible funct…

Antiamoebics, Anti-Cancer Agent, Anti-Obesity Agent

Novel ovalicin analog compounds with MetAP2 inhibitory activity show therapeutic effects on various …