Development of Molecular Targeted and Nucleic Acid Therapeutics for C11orf97
Erythromycin binds to CUG-expanded RNA to suppress RNA toxicity and splicing misregulation in DM1.
Life-extending effects confirmed in mice by using the sensor molecule CtBP2, which has broad metabol…
Upstream Stop Codon Insertion to Suppress CAG Repeat–Driven Disease Progression
Suppression of epidermal cell death through control of necroptosis by chenodeoxycholic acid
Suitable for patients with comorbidities
This mycobacterial glycolipid compound is an adjuvant and antigen that activates T cells, being expe…
Substance derived from seaweed “Padina extract” 2-hydroxypentanoic acid
Inhibitor of the integrin αV‒CTGF axis, which is activated in response to increased hepatic sinusoid…
Discovery of a new mechanism of hypertension induction and proposal for drug discovery collaboration…