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Therapeutic-drug

Macrophages as Drug Targets for Hypertension Treatment

Discovery of a new mechanism of hypertension induction and proposal for drug discovery collaboration…

Therapeutics for Fibrosis Targeting RIG-I

A drug candidate for the treatment of various fibrosis, incorporating a ligand for RIG-I, a pattern …

Cancer Metastasis Inhibitor

Target molecules and their inhibitors that control the survival and reactivation of disseminated tum…

Rett Syndrome Therapeutic Drug

We have recently discovered that an already approved small-molecule therapeutic drug is effective ag…

Collaborative Development of Therapeutic Medicine for Infectious Disea...

Small Molecule enhances Claudin-5 (CLDN5) function, which organizes tight junctions between vascular…

Enhancer of Anticancer Drug Taxanes

Small molecules that enhance the microtubule polymerization-promoting activity of anticancer drug ta…

Fusion Protein Anticancer Drug Targeting RAS

Fusion protein X, which combines a RAS-binding domain, a cell membrane-permeable peptide, and a thir…

Development of Phosphate Prodrug Compounds of Nucleic Acid Analogues

Development of fluoride-type phosphate prodrugs bearing fluorophosphoramidate as biocompatible funct…

Antiamoebics, Anti-Cancer Agent, Anti-Obesity Agent

Novel ovalicin analog compounds with MetAP2 inhibitory activity show therapeutic effects on various …

Thyroid Hormone Receptor-beta (THRβ) Selective Agonist

A small molecule compound that is superior to existing thyroid hormone (TH) analog compounds and app…