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Therapeutic-drug

Development of Novel Therapeutic Agent for LKB1-Inactivated Lung Cance...

An innovative therapeutic approach for refractory LKB1-inactivated lung cancer using next-generation…

Small molecule compounds that facilitate drug delivery to the brain

A Next-Generation Platform Technology Dramatically Enhancing Brain Delivery of Small and Medium-Mole…

Anti-PF4 mAb: selectively targeting tumor-associated Tregs

Avoiding immune-related adverse events (irAEs) by locally inhibiting Th1-Treg differentiation in the…

Protein Therapeutics (VWA5A) for Treatment and Prevention of Sepsis

Supplementation of VWA5A, an anti-inflammatory DAMP released during pyroptosis, prevents organ damag…

GBF1-targeted broad-spectrum antiviral nucleic acid therapeutics

A novel concept that targets GBF1, a host factor shared by diverse RNA viruses, to enable broad-spec…

A candidate compound for promoting bone formation

Bone volume was increased through the enhanced bone formation in vivo, and the mechanism of action i…

Tolvaptan Silicon Analogues with Markedly Enhanced Brain Penetration

Novel silicon-containing analogues of tolvaptan, created by replacing a ring carbon with silicon (ca…

Novel Therapeutic for Triazole-Resistant Pulmonary Aspergillosis

A combination therapy of an existing triazole and low-dose Luliconazole restores drug sensitivity in…

Novel FAPα-Targeted Radiopharmaceutical

A therapeutic agent targeting refractory solid tumors such as pancreatic cancer and triple-negative …

LNP-DDS for Pancreatic Islet β-Cells

Achieving highly efficient drug delivery to pancreatic islets through phospholipid selection and par…