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Therapeutic-drug

Novel Therapeutic Target to Overcome Resistance to Multi-Kinase Inhibi...

Targeting TKI-Induced GTP Metabolic Dependency: Enhancing Lenvatinib Sensitivity via IMPDH Inhibitio…

Mitochondrial Disease Treatment Drugs

Highly selective genome editing RNP (Cas9 protein-gRNA complex) targeting mutant mtDNA (mitochondria…

A Therapeutic Agent for HFpEF: Tamibarotene (AM80)

A Novel Mechanism that Induces Meflin Expression, Controls the Fate of Fibroblasts to Suppress Fibro…

11-Amino-Acid Antifungal Peptide Drug from Plant Defensins

Expected to be effective against a wide range of fungal species through a mechanism of action differ…

Therapeutic antibodies targeting Myl9/12 for chronic inflammatory dise...

A new therapeutic concept to prevent cellular infiltration into inflamed tissues by targeting the ne…

Therapeutic antibody targeting Clec12b specifically expressed in skin ...

Treatment of allergies and mastocytoma with Mast cell targeting antibodies

Therapeutic Drug for Achondroplasia

The approved antihistamine meclizine promotes cartilage formation by suppressing excessive signaling…

NF-κB inducing kinase (NIK); Novel target for cholangiocarcinoma

Molecular targeted drugs targeting the NIK associated with the differentiation factor from hepatocyt…

A new concept for the treatment of allergic dermatitis by targeting gl...

Inhibition of TLR4-dependent allergic inflammatory response by Asialoglycoprotein receptor (Asgr1) g…

IBD treatment by intestinal administration of human iPS cell-derived o...

A mechanism for promoting intestinal tissue regeneration by direct administration of high-quality in…